Non - linear Growth Kinetics of Breast Cancer Stem Cells : Implications for Cancer
نویسندگان
چکیده
Western Blot analysis. Protein concentration was measured using BCA kit (Thermo Scientific, Rockford, IL, USA) and protein lysates were separated by SDS-PAGE and then blotted onto Hybond-C extra membranes (GE Healthcare, Buckinghamshire, UK) for Western blot analysis. Antigen-antibody reaction was detected using Super Signal West Pico and Femto chemiluminescent substrate kits according to manufacturer’s instructions (Thermo Scientific). The primary antibodies used for Western blot analysis are purchased from Cell Signaling Technology (Beverly, MA).
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Nonlinear Growth Kinetics of Breast Cancer Stem Cells: Implications for Cancer Stem Cell Targeted Therapy
Cancer stem cells (CSCs) have been identified in primary breast cancer tissues and cell lines. The CSC population varies widely among cancerous tissues and cell lines, and is often associated with aggressive breast cancers. Despite of intensive research, how the CSC population is regulated within a tumor is still not well understood so far. In this paper, we present a mathematical model to expl...
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